Brain-Heart Interplay
Biological systems like brain and heart are "complex", meaning that, due to the interaction of many sub-components, the body-system demonstrates properties that the individual components acting alone cannot.
Brain-Heart Interplay
Biological systems like brain and heart are "complex", meaning that, due to the interaction of many sub-components, the body-system demonstrates properties that the individual components acting alone cannot. Through their dynamical interplay, the brain and the heart ensure fundamental homeostasis and mediate several physiological functions as well as their disease-related aberrations. Indeed, while clinical evidence points to the functional interplay between brain and body, a solid comprehensive data modelling/processing framework linking the very different physiological dynamics but bound to the same systemic biological responses despite time-scale differences is the main purpose of this research activity. In this context, we are currently focused on
- Development of new computational models of brain-heart joint dynamics
- Development of new metrics for brain-heart interplay
- The study of brain-heart interaction using advanced computational models for synchronized EEG/fMRI and heartbeat dynamics
- Development of novel Brain-Heart Computer Interfaces, also for affective computing and neurorehabilitation applications
- Exploitation of state-of-the-art brain-heart interplay metrics in clinical scenario, such as, but not limited to, psychiatry, neurology, and psychology.
Candia-Rivera, Diego, et al. "The Role of Electroencephalography Electrical Reference in the Assessment of Functional Brain–Heart Interplay: From Methodology to User Guidelines." Journal of Neuroscience Methods (2021): 109269.
Catrambone, Vincenzo, et al. "Intensification of functional neural control on heartbeat dynamics in subclinical depression." Translational Psychiatry 11.1 (2021): 1-10.
Valenza, Gaetano, et al. "Uncovering complex central autonomic networks at rest: a functional magnetic resonance imaging study on complex cardiovascular oscillations." Journal of the Royal Society Interface 17.164 (2020): 20190878.
Catrambone, Vincenzo, et al. "Time-resolved directional brain–heart interplay measurement through synthetic data generation models." Annals of biomedical engineering 47.6 (2019): 1479-1489.
Valenza, Gaetano, et al. "Combining electroencephalographic activity and instantaneous heart rate for assessing brain–heart dynamics during visual emotional elicitation in healthy subjects." Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences 374.2067 (2016): 20150176.